Fluzone® High-Dose Influenza Vaccine
نویسندگان
چکیده
منابع مشابه
Influenza Virus Vaccine Fluzone
DESCRIPTION Fluzone, Influenza Virus Vaccine, (Zonal Purified, Subvirion) for intramuscular use, is a sterile suspension prepared from influenza viruses propagated in chicken embryos. The virus-containing fluids are harvested and inactivated with formaldehyde. Influenza virus is concentrated and purified in a linear sucrose density gradient solution using a continuous flow centrifuge. The virus...
متن کامل1059Expanded immunogenicity of high-dose inactivated influenza vaccine compared to standard-dose inactivated influenza vaccine in older adults
Background. Previous studies have demonstrated the superior immunogenicity of high-dose inactivated influenza vaccine (IIV-HD) in older adults compared to standard-dose inactivated influenza vaccine (IIV-SD), as measured by hemagglutination inhibition (HAI) antibody titers against egg-propagated vaccine antigens. The 20122013 northern hemisphere influenza season was characterized by high H3N2 a...
متن کاملAcceptability of fluzone intradermal vaccine to patients and vaccine administrators.
CONTEXT Fluzone Intradermal (ID) vaccine was licensed in the United States in May 2011 and uses a microinjection device with a 1.5-mm, 30-gauge needle that delivers a smaller volume and antigen load than the Fluzone Intramuscular (IM) vaccine. The same ID microinjection system has been used in Argentina and Australia since 2010 with documented acceptance by both patients and vaccine administrat...
متن کامل530Disease Modulation in Older Adults Vaccinated with High-Dose Versus Standard-Dose Influenza Vaccine
Background. High-dose inactivated influenza vaccine (IIV-HD) induces higher antibody responses and provides improved protection against influenza illness compared to a standard-dose vaccine (IIV-SD) in older adults. We evaluated its impact on disease modulation. Methods. A multicenter, randomized, double-blind, active-controlled trial compared IIV-HD (60 μg of hemagglutinin [HA] per strain) to ...
متن کاملMF59-adjuvanted influenza vaccine (FLUAD®) elicits higher immune responses than a non-adjuvanted influenza vaccine (Fluzone®): A randomized, multicenter, Phase III pediatric trial in Mexico
The poor immune response elicited by trivalent influenza vaccines (TIVs) in children can be enhanced by the addition of adjuvants. This observer-blind, randomized Phase III trial assessed the immunogenicity and safety of the MF59-adjuvanted trivalent influenza vaccine FLUAD® (aTIV) and a non-adjuvanted TIV, in healthy children (aged 6 to <72 months) from 3 centers in Mexico, during the 2014-201...
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ژورنال
عنوان ژورنال: Expert Review of Vaccines
سال: 2016
ISSN: 1476-0584,1744-8395
DOI: 10.1080/14760584.2016.1254044